Top Smoke or Cannabis-Related Businesses in South Carolina 2026 No Program

Short answer: South Carolina has 196 smoke or cannabis-related businesses listed in our 2026 directory, including 25 dispensaries, 83 smoke shops, 28 CBD stores, 4 brands, and 1 delivery services. Filter by category, browse by city, or see compliance regulations below.

196

Smoke or cannabis-related businesses

25

Dispensaries

4

Cannabis brands

1

Delivery services

4.7★

Average rating

View South Carolina cannabis regulations →

Cities in South Carolina

Greenville 28 listings Myrtle Beach 26 listings Rock Hill 25 listings Columbia 23 listings Charleston 21 listings Summerville 19 listings Spartanburg 17 listings Florence 14 listings Mount Pleasant 12 listings North Charleston 11 listings

Businesses in South Carolina

High Tide Hemp Dispensary — Dispensaries in Charleston, SC

High Tide Hemp Dispensary

Charleston, South Carolina

★★★★★5.0(Google)

Weed & Cannabis Delivery Dispensary

Charleston, South Carolina

★★★★★5.0

High Market Organics — Dispensaries in Mount Pleasant, SC

High Market Organics

Mount Pleasant, South Carolina

★★★★★5.0(Google)

High Standard Cannabis — Dispensaries in Greenville, SC

High Standard Cannabis

Greenville, South Carolina

★★★★★5.0(Google)

101 Smoke Shop - Columbia - Senate St. — Smoke Shop in Columbia, SC

101 Smoke Shop - Columbia - Senate St.

Columbia, South Carolina

★★★★★5.0(Google)

University Tobacco & Vapor — Smoke Shop in North Charleston, SC

University Tobacco & Vapor

North Charleston, South Carolina

★★★★★5.0(Google)

843 Smoke & Tobacco — Smoke Shop in Mount Pleasant, SC

843 Smoke & Tobacco

Mount Pleasant, South Carolina

★★★★★5.0(Google)

SHEM CREEK SMOKES — Smoke Shop in Mount Pleasant, SC

SHEM CREEK SMOKES

Mount Pleasant, South Carolina

★★★★★5.0(Google)

Cloudz Smoke Shop — Smoke Shop in Greenville, SC

Cloudz Smoke Shop

Greenville, South Carolina

★★★★★5.0(Google)

Your CBD Store | SUNMED - Columbia, SC — CBD Store in Columbia, SC

Your CBD Store | SUNMED - Columbia, SC

Columbia, South Carolina

★★★★★5.0(Google)

Midland CBD and Oils — CBD Store in Columbia, SC

Midland CBD and Oils

Columbia, South Carolina

★★★★★5.0(Google)

I Heart CBD - Mount Pleasant — CBD Store in Mount Pleasant, SC

I Heart CBD - Mount Pleasant

Mount Pleasant, South Carolina

★★★★★5.0(Google)

SOUTHERN PURE CO — Hemp Business in Charleston, SC

SOUTHERN PURE CO

Charleston, South Carolina

★★★★★5.0(Google)

Elevate CBD and Wellness — Ancillary Services in Rock Hill, SC

Elevate CBD and Wellness

Ancillary Services

Rock Hill, South Carolina

★★★★★5.0(Google)

Yerba Cannabis Collective — Ancillary Services in Rock Hill, SC

Yerba Cannabis Collective

Ancillary Services

Rock Hill, South Carolina

★★★★★5.0(Google)

High Score — Ancillary Services in Myrtle Beach, SC

High Score

Ancillary Services

Myrtle Beach, South Carolina

★★★★★5.0(Google)

Delta Dreaming — Ancillary Services in Myrtle Beach, SC

Delta Dreaming

Ancillary Services

Myrtle Beach, South Carolina

★★★★★5.0(Google)

Your CBD Store - Spartanburg, SC — CBD Store in Spartanburg, SC

Your CBD Store - Spartanburg, SC

Spartanburg, South Carolina

★★★★★5.0(Google)

Stoneys Smoke Shop — Smoke Shop in Rock Hill, SC

Stoneys Smoke Shop

Rock Hill, South Carolina

★★★★★5.0(Google)

Cherry smoke shop — Smoke Shop in Rock Hill, SC

Cherry smoke shop

Rock Hill, South Carolina

★★★★★5.0(Google)

Your CBD Store | SUNMED - Myrtle Beach, SC — CBD Store in Myrtle Beach, SC

Your CBD Store | SUNMED - Myrtle Beach, SC

Myrtle Beach, South Carolina

★★★★★5.0(Google)

Carolina CBD Pharmacy — CBD Store in Myrtle Beach, SC

Carolina CBD Pharmacy

Myrtle Beach, South Carolina

★★★★★5.0(Google)

Carolina Bud Dispensary — Dispensaries in Spartanburg, SC

Carolina Bud Dispensary

Spartanburg, South Carolina

★★★★★5.0(Google)

CBD of Florence — CBD Store in Florence, SC

CBD of Florence

Florence, South Carolina

★★★★★5.0(Google)

Inlet Dispensary — Dispensaries in Myrtle Beach, SC

Inlet Dispensary

Myrtle Beach, South Carolina

★★★★★5.0(Google)

CannaBetter.Farm Ltd. Co Dispensary Murrells Inlet — Dispensaries in Myrtle Beach, SC

CannaBetter.Farm Ltd. Co Dispensary Murrells Inlet

Myrtle Beach, South Carolina

★★★★★5.0(Google)

Smoker's Republic — Headshop in Summerville, SC

Smoker's Republic

Summerville, South Carolina

★★★★★5.0(Google)

Filthy Palate Cigar Shop & Lounge — Smoke Shop in Summerville, SC

Filthy Palate Cigar Shop & Lounge

Summerville, South Carolina

★★★★★5.0(Google)

Breeze Smoke Shop — Smoke Shop in Spartanburg, SC

Breeze Smoke Shop

Spartanburg, South Carolina

★★★★★5.0(Google)

864 Smoke & Vape

Spartanburg, South Carolina

★★★★★5.0(Google)

I SMOKE 1 TOBACCO & VAPE — Smoke Shop in Florence, SC

I SMOKE 1 TOBACCO & VAPE

Florence, South Carolina

★★★★★5.0(Google)

Viva Smoke & Vape — Headshop in Florence, SC

Viva Smoke & Vape

Florence, South Carolina

★★★★★5.0(Google)

Mister B — Dispensaries in Charleston, SC

Mister B

Charleston, South Carolina

★★★★★5.0(Google)

Green 21 Hemp & Lifestyle — Hemp Business in Myrtle Beach, SC

Green 21 Hemp & Lifestyle

Myrtle Beach, South Carolina

★★★★★5.0(Google)

I Heart CBD - Johns Island

North Charleston, South Carolina

★★★★★5.0(Google)

Your CBD Store | SUNMED - Lexington, SC — Hemp Business in Columbia, SC

Your CBD Store | SUNMED - Lexington, SC

Columbia, South Carolina

★★★★★5.0(Google)

Redeem Therapeutics — Hemp Business in Columbia, SC

Redeem Therapeutics

Columbia, South Carolina

★★★★★5.0(Google)

The Ultimate pre rolls and hash and vape pens and joints and edibles store

Charleston, South Carolina

★★★★★5.0(Google)

Healrain CBD

Mount Pleasant, South Carolina

★★★★★5.0(Google)

Arcanna Dispensary — Dispensaries in Charleston, SC

Arcanna Dispensary

Charleston, South Carolina

★★★★★4.9(Google)

Charleston Hemp Collective — Dispensaries in Charleston, SC

Charleston Hemp Collective

Charleston, South Carolina

★★★★★4.9(Google)

Arcanna Dispensary — Dispensaries in Charleston, SC

Arcanna Dispensary

Charleston, South Carolina

★★★★★4.9(Google)

Illuminati Glass Gallery & Smoke Shop — Smoke Shop in Columbia, SC

Illuminati Glass Gallery & Smoke Shop

Columbia, South Carolina

★★★★★4.9(Google)

540 SMOKE & VAPE NORTH CHARLESTON — Smoke Shop in North Charleston, SC

540 SMOKE & VAPE NORTH CHARLESTON

North Charleston, South Carolina

★★★★★4.9(Google)

PUFF STUFF SMOKE & VAPE — Smoke Shop in North Charleston, SC

PUFF STUFF SMOKE & VAPE

North Charleston, South Carolina

★★★★★4.9(Google)

843 Smoke & Vape MP — Smoke Shop in Mount Pleasant, SC

843 Smoke & Vape MP

Mount Pleasant, South Carolina

★★★★★4.9(Google)

The Holistic Company of Greenville, LLC.

Greenville, South Carolina

★★★★★4.9(Google)

Your CBD Store | SUNMED - Irmo, SC — CBD Store in Columbia, SC

Your CBD Store | SUNMED - Irmo, SC

Columbia, South Carolina

★★★★★4.9(Google)

KYLÉ Smoke Shop - Greenville — Smoke Shop in Greenville, SC

KYLÉ Smoke Shop - Greenville

Greenville, South Carolina

★★★★★4.9(Google)

I Heart CBD - Centre Pointe — CBD Store in North Charleston, SC

I Heart CBD - Centre Pointe

North Charleston, South Carolina

★★★★★4.9(Google)

Featured product · Cannabis PromotionsAd

Custom 1¼ Rolling Papers — Fully Customized Booklet

Custom 1¼ Rolling Papers — Fully Customized Booklet

As low as $0.69 · ~6-week lead time

Fully customized 1¼ booklets — cover to leaf.

Get a free quote →

Cannabis in South Carolina

South Carolina has no legal cannabis program, whether medical or recreational, making it one of the most restrictive states in the country regarding marijuana. All forms of cannabis remain illegal under state law, though hemp-derived CBD products compliant with the 2018 Farm Bill are available at retail locations. CBD shops, smoke shops, and wellness stores sell hemp-derived products in Charleston, Columbia, Greenville, and other cities. Medical cannabis legislation has been introduced but has not advanced to passage.

Cannabis Promotions supplies cannabis businesses with custom branded accessories — lighters, grinders, rolling papers, rolling trays, and doob tubes — at wholesale pricing. Get custom branded products for your South Carolina cannabis business →

Frequently Asked Questions — Cannabis in South Carolina

Is cannabis legal in South Carolina?

No, all forms of cannabis are illegal in South Carolina. There is no medical or recreational program, though hemp-derived CBD products are available.

Can I buy CBD products in South Carolina?

Yes, hemp-derived CBD products with less than 0.3% THC are legal and sold at smoke shops, CBD stores, and wellness retailers throughout the state.

Are there dispensaries in South Carolina?

No, there are no cannabis dispensaries in South Carolina. Only hemp and CBD retailers operate in the state.

Is South Carolina considering medical cannabis?

Medical cannabis bills have been introduced in the South Carolina legislature with some bipartisan support, but none have been signed into law.

Listings & accuracy: Business listings are aggregated from public sources and user submissions and may be inaccurate, incomplete, or out of date. Inclusion is not an endorsement, and Cannabis Promotions does not independently verify the licensing or legal status of listed businesses — always confirm directly with the business and the relevant state or provincial regulator. Reviews reflect the views of their authors, not Cannabis Promotions.

Not professional advice: Content is provided for general informational purposes only and does not constitute legal, financial, tax, or other professional advice.

Age & products: You must be 21 or older to use this site. Cannabis Promotions provides custom branding, merchandise, and packaging products only — we do not sell, distribute, or facilitate the sale of cannabis, THC, or any controlled substance.